Wonder
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Research Outline
Prepared for Ann S. | Delivered May 22, 2020
Best Natural Supplements: Aromatase Inhibitors
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Goals
To identify the best natural supplements to block aromatase, what doses are therapeutic, and any differences in the effects for men and women, as well as the symptoms of high aromatase activity and the causes.
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Early Findings
Causes of High Aromatase Activity
Aromatic activity increases with
age
, the amount of fatty tissue present in the body, poor nutrition, and weight gain, as well as a lack of exercise and high-stress levels.
People who suffer from
Metabolic Hypothyroidism
also tend to have high aromatase activity.
Aromatase excess syndrome, also known as increased aromatase activity, is a condition caused by the rearrangement of genetic material containing the
CYP19A1 gene
.
Genetic restructuring
causes an increase in aromatase production by altering the activity of the gene.
Interestingly, scientists have linked aromatase to the development of
cancer
, autoimmunity, and other chronic diseases.
Symptoms
Males with aromatase excess syndrome often experience
breast enlargement
(gynecomastia) either during late childhood or adolescence.
Their bones also develop more rapidly and stop growing sooner than usual. As such, affected males usually have a
short adult stature
.
While females rarely exhibit symptoms, aromatase excess syndrome can also lead to breast enlargement (macromastia), short stature, and
irregular periods
.
Natural Aromatase Inhibitors
Some foods serve as aromatase inhibitors in both men and women. They include
celery
, red wine, olive oil, white button mushrooms, oysters, cruciferous vegetables, and parsley.
Grape seed extract
is a natural aromatase inhibitor or estrogen blocker for postmenopausal women with a high risk of breast cancer. However, men may use the same and experience similar benefits when taking it as a supplement.
Other natural aromatase inhibitors include maca,
chrysin
, and wild nettle root.
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