Best Natural Supplements: Aromatase Inhibitors


To identify the best natural supplements to block aromatase, what doses are therapeutic, and any differences in the effects for men and women, as well as the symptoms of high aromatase activity and the causes.

Early Findings

Causes of High Aromatase Activity

  • Aromatic activity increases with age, the amount of fatty tissue present in the body, poor nutrition, and weight gain, as well as a lack of exercise and high-stress levels.
  • People who suffer from Metabolic Hypothyroidism also tend to have high aromatase activity.
  • Aromatase excess syndrome, also known as increased aromatase activity, is a condition caused by the rearrangement of genetic material containing the CYP19A1 gene.
  • Genetic restructuring causes an increase in aromatase production by altering the activity of the gene.
  • Interestingly, scientists have linked aromatase to the development of cancer, autoimmunity, and other chronic diseases.


  • Males with aromatase excess syndrome often experience breast enlargement (gynecomastia) either during late childhood or adolescence.
  • Their bones also develop more rapidly and stop growing sooner than usual. As such, affected males usually have a short adult stature.
  • While females rarely exhibit symptoms, aromatase excess syndrome can also lead to breast enlargement (macromastia), short stature, and irregular periods.

Natural Aromatase Inhibitors

  • Some foods serve as aromatase inhibitors in both men and women. They include celery, red wine, olive oil, white button mushrooms, oysters, cruciferous vegetables, and parsley.
  • Grape seed extract is a natural aromatase inhibitor or estrogen blocker for postmenopausal women with a high risk of breast cancer. However, men may use the same and experience similar benefits when taking it as a supplement.
  • Other natural aromatase inhibitors include maca, chrysin, and wild nettle root.

Proposed next steps:

You need to be the project owner to select a next step.