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Research Outline
Prepared for Simon H. | Delivered January 11, 2020
Patients with Chronic Disease
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Goals
To provide the number of patients in the United States who had, or currently live with Multiple Sclerosis, Rheumatoid Arthritis, and Inflammatory Bowel Disease.
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Early Findings
Multiple Sclerosis
In 2017, the National MS Society reported that up to an estimated up to
913,925 Americans
were living with Multiple Sclerosis.
That represents a
prevalence rate
of up to 363 per 100,000 Americans.
According to the MS Discovery Forum, around
200 new cases
of Multiple Sclerosis are diagnosed in the US each week.
While Multiple Sclerosis can develop at any time, most Americans are between
20 and 50 years old
when they are diagnosed.
Multiple Sclerosis prevalence and diagnosis rates vary according to geographic region and are higher in regions farther away from the equator. As a result, states in the northern United States have a
higher prevalence rate
(110-140 per 100,000 people) than states in the southern United States (57-78 per 100,000 people).
85%
of Americans diagnosed with Multiple Sclerosis are diagnosed with RRMS (Relapse-Remitting Multiple Sclerosis).
In most cases, Multiple Sclerosis does not cause death. Life expectancy for people who have Multiple Sclerosis ranges from the same as someone who does not have the disease, to shorter by six or seven years. In
extremely rare cases
, MS can progress rapidly and be fatal.
Central New York
has the highest prevalence of Multiple Sclerosis in the nation. Syracuse, for example, has a prevalence rate that is roughly twice the national average.
Rheumatoid Arthritis (RA)
Rheumatoid Arthritis is the
third most common
type of arthritis diagnosed in the United States, behind gout and osteoarthritis, with
over 1.3 million
people affected by it.
The annual incidence rate of RA in the United States is
40
new cases diagnosed per 100,000 people,
lower
than many other countries.
Between 2017 and 2027, the US is expected to have one of the
highest annual growth rates
for new cases of RA. This will primarily be due to changes in the US population as a result of immigration.
Women make up approximately
75%
of people who have RA.
The prevalence of RA
varies greatly among populations
and ethnic groups, with people of Asian descent having the lowest rates and certain Native American tribes having the highest.
While Rheumatoid Arthritis doesn't usually cause death on its own, it can cause
complications
like heart disease, lung disease, infections, and musculoskeletal conditions, that can lead to death.
Inflammatory Bowel Disease (IBD)
Inflammatory Bowel Disease
is the group name for
two related diseases
: Crohn's disease and ulcerative colitis.
In 2015, an estimated
3 million adults
(
1.3%
of the US population), stated they had been diagnosed with IBD.
In 2016,
1 in 209
adults and
1 in 1299
children aged 2-17 had IBD
Adults are most commonly diagnosed with IBD while in their
20s and 30s
.
According to the
NCBI
, the most recent estimates of the prevalence of IBD in the IS were based on data gathered in 2009.
The pediatric prevalence rate for IBD grew by
133%
between 2007 and 2016.
The adult prevalence rate for IBD grew by
123%
between 2007 and 2016.
During this time frame,
boys
were more likely to be diagnosed with IBD than girls. Among adults,
women
are more likely to be diagnosed than men.
Data gathered between 2003 and 2007 has been used to forecast future IBD prevalence rates. It is estimated that the prevalence rate of IBD will be
four to six times higher
in 2030 than it was in 2003.
It is also estimated that the IBD will experience an average annual percent change of
5%
each year through 2030.
While people who have IBD often have a
shorter life span
and higher mortality rate than people without it, it
can not be proven
that IBD is the reason why that is. Complications of IBD such as developing liver disease or toxic megacolon could also be important factors.
Cancer
Information about the number of patients in the United States who had, or currently live with Cancer was provided in the first request.
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