Use of magnesium sulphate has been shown to be helpful in managing acute cases of trichothecene toxicity in pigs.
This treatment is more effective when used together with activated charcoal.
This involves the use of an enzyme derived from bacteria to de-epoxidize the trichothecene. The chemical structure of trichothecenes is made up of the 12,13-epoxy-trichothec-9-ene nucleus. The 12,13-epoxide ring is responsible for their toxicity and damages to cells.
De-epoxidation is the degradation of the trichothecene’s epoxide group.
The process by which this occurs is called biotransformation and deoxynivalenol is converted to deepoxydeoxynivalenol.
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